Dr. Marjan Motiei
Wissenschaftliche Mitarbeiterin, Schwerpunkt Forschung
Arbeitsgruppe Prof. Dr. med. Chalid Assaf

Fon: 040.361 226 40
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Biographie

Dr. Marjan Motiei holds a BSc in Microbiology from Esfahan University, an MSc in Biochemistry from Tehran University, and a Ph.D. in Biochemistry from Razi University in Iran. After completing her education, she pursued postdoctoral research at the Royan Institute for Biotechnology (2017 to 2018) and later served as a postdoc and research associate at Toma Bata University (TBU) in the Czech Republic, specializing in nanomedicine (2018 to 2023). Since September 2023, Dr. Motiei has been a Research Associate at the Medical School Hamburg (MSH).

Teaching activities

Dr. Motiei has extensive teaching experience, having lectured in microbiology and biochemistry at Sahreza University, Esfahan, Iran (2012-2017) and biochemistry and Physiology at Golpaygan University, Esfahan, Iran (2017-2018). At Toma Bata University (TBU), she supervised the scientific work of Ph.D. and MSc students.

Research

Dr. Motiei's primary research focus is nanomedicine, particularly enhancing the therapeutic effects of anticancer compounds. She specializes in synthesizing polymeric nanostructures and hydrogels, and developing targeted delivery systems for various therapeutics. Currently, her research is concentrated on two methods for treating cutaneous T cell lymphoma: chronotherapy and targeted delivery of therapeutics through hydrogel.

Publikationen

  • Motiei M.,* Mišík O., Truong T.H., Lizal F., Humpolíček P., Sedlařík V., Sáha P. (2023) Engineering of inhalable nano-in-microparticles for co-delivery of small molecules and miRNAs. Discover Nano 18 (1), 38
  • Yadollahi Z., Motiei M.,* Kazantseva N., Císař J., Sáha P. (2023) Whey Protein Isolate-Chitosan PolyElectrolyte Nanoparticles as a Drug Delivery System. Molecules: 28 (4), 1724
  • Motiei M.,* Lucia LA., Sáha T., Sáha P. (2023) Current state-of-the-art review of nanotechnology-based therapeutics for viral pandemics: Special attention to COVID-19. Nanotechnology Reviews: 12 (1), 1- 25
  • Zandraa, O.,* Ngwabebhoh, F. A.,* Patwa, R., Nguyen, H. T., Motiei, M., Saha, N., Saha, T., Saha, P. (2021) Development of dual crosslinked mumio-based hydrogel dressing for wound healing application: Physico-chemistry and antimicrobial activity. International Journal of Pharmaceutics: 120952.
  • Motiei M., Aboutalebi F., Forouzanfar M., Dormiani K., Nasr-Esfahani M.H.*, Mirahmadi- Zare S.Z.*(2021) Smart co-delivery of miR-34a and cytotoxic peptides (LTX-315 and melittin) by chitosan basedpolyelectrolyte nanocarriersforspecific cancer cell death induction, Materials Science and Engineering:C, 112258.
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  • Motiei M., Mirahmadi-Zare S.Z.,* Nasr-Esfahani MH. (2021) Chemical Stabilization of γ-Polyglutamate by Chitosan and the effect of co-solvents on the stability. Biophysical Chemistry. 275, 106605.
  • Motiei M.,* Pleno de Gouveia L., Šopík T., Vícha R.t, Škoda D., Císaˇr J., Khalili R., Domincová Bergerová E., Münster L., Fei H., Sedlaˇrík V., Sáha P. (2021) Nanoparticle-Based Rifampicin Delivery System Development. Molecules. 26, 2067.
  • Motiei M., * Vaculikova K., Cela A., Tvrdonova K., Khalili R., Rumpik D., Rumpikova T., Glatz Z., Saha T. (2020): Non-Invasive Human Embryo Metabolic Assessment as a Developmental Criterion. Journal of Clinical Medicine. 9 (12), 4094.  
  • Rezaei S., Kashanian S.,* Bahrami Y., Cruz L.J., Motiei M. (2020): Redox-sensitive and hyaluronic acid functionalized nanoparticles for improving breast cancer treatment by cytoplasmic 17α- Methyltestosterone delivery. Molecules. 25, 1181.
  • Motiei M.,* Sedlařík V., Lucia L.A., Fei H., Münster L. (2020): Stabilization of Chitosan- Based Polyelectrolyte Nanoparticle Cargo Delivery Biomaterials by a Multiple Ionic Cross- Linking Strategy. Carbohydrate Polymers, p. 115709.
  • Kashanian S.,* Azandaryani A.H., Shahlaei M., Derakhshandeh K., Motiei M., Moradi S. (2019): A comprehensive physicochemical, in vitro and molecular characterization of letrozole incorporated chitosan-lipid nanocomplex. Pharmaceutical research, 36(4), 62.
  • Motiei M., Kashanian S.,* Lucia A.L., Khazaei M. (2017): Intrinsic Parameters for the Synthesis and Tuned Properties of Amphiphilic Chitosan Drug Delivery Nanocarriers, Journal of controlled release, 260, 213–225.
  • Motiei M., Kashanian S.* (2017): Novel Amphiphilic Chitosan Nanocarriersfor Sustained Oral Delivery of Hydrophobic Drugs, European Journal of Pharmaceutical Sciences, 99, 285–291.
  • Motiei M., Kashanian S.,* Taherpour A. (2016): Hydrophobic amino acids grafted onto chitosan: a novel amphiphilic chitosan nanocarrier for hydrophobic drugs, Drug Development and Industrial Pharmacy, 43(1), 1-11.
  • Motiei M., Kashanian S.* (2017): Preparation of Amphiphilic Chitosan Nanoparticles for Controlled Release ofHydrophobic Drugs, Journal ofNanoscience andNanotechnology, 17(8), 5226-5232.
  • Motiei M., Kashanian S.,* Azandaryani A.H. (2017): Effect of Fabrication Parameters on the Physiochemical Properties of Amphiphilic Chitosan Nanoparticles, Iranian Journal of Science and Technology Transaction A: Science, 42(4), 1873-1879.
  • Motiei M., Tavalaee M., Rabiei F., Hajihosseini R., Nasr-Esfahani M. H*. (2013): Evaluation of HSPA2 in fertile and infertile individuals, Andrologia. 45(1):66-72.