Dr. Maibritt Kretschmer
Research assistant, focus on research
Project by Prof. Dr. Sven Hendrix
Phone: 040.361 226 43264
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Biography
Maibritt Kretschmer studied Biotechnology at the bachelor’s level and Pharmaceutical Biotechnology at the master’s level at the Hamburg University of Applied Sciences (HAW; 2013–2018). She subsequently completed her doctoral studies at Ludwig Maximilian University of Munich (LMU) in the research group of Prof. Zahler in the field of Pharmaceutical Biology. Her project focused on mechanotransduction of the Notch signaling pathway in endothelial cells, modulated by the stiffness of the extracellular matrix. During a one-year postdoctoral appointment, her doctoral research was further expanded, allowing her to gain additional expertise in angiogenesis models, endothelial spheroids, and extracellular matrix remodeling.
She also gained teaching experience as a teaching assistant in the “Fundamentals of Biology” laboratory course for Pharmaceutical Sciences students and supervised several successful thesis projects.
Since September 2023, Maibritt Kretschmer has been working as a postdoctoral researcher in the Hendrix research group, with a focus on the development of cerebral organoid models. She also organizes the networking meeting “Organoids in the North” and is a member of the organizing committee of the international CAOS Symposium (Conference on Advancements in Organoid Sciences).
Publications
- Kretschmer, M.; Vollmar, A. M.; Zahler, S. (2025) Endothelial sprout formation is regulated by substrate stiffness and Notch signaling. International Journal of Molecular Sciences 26(7): 10.3390/ ijms26073155.
- Kretschmer, M.; Mamistvalov, R.; Sprinzak, D.; Vollmar, A. M.; Zahler, S. (2023) Matrix stiffness regulates Notch signaling activity in endothelial cells. Journal of Cell Science 136(2): 10.1242/ jcs.260442.
- Wang, P.; Klassmüller, T.; Karg, C. A.; Kretschmer, M.; Zahler, S.; Braig, S.; Bracher, F.; Vollmar, A. M.; Moser, S. (2022) Using the yeast three-hybrid system for the identification of small molecule-protein interactions with the example of ethinylestradiol. Biological Chemistry 403(4): 10.1515/hsz-2021-0355.
- Kretschmer, M.; Rüdiger, D.; Zahler, S. (2021) Mechanical Aspects of Angiogenesis. Cancers 13(19): 10.3390/ cancers13194987.
- Zisis, T.; Schwarz, J.; Balles, M.; Kretschmer, M.; Nemethova, M.; Chait, R.; Hauschild, R.; Lange, J.; Guet, C.; Sixt, M.; Zahler, S. (2021) Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control. ACS Applied Materials & Interfaces: 10.1021/ acsami.1c09850.
- Karg, C. A.; Wang, S.; Al Danaf, N.; Pemberton, R. P.; Bernard, D.; Kretschmer, M.; Schneider, S.; Zisis, T.; Vollmar, A. M.; Lamb, D. C.; Zahler, S.; Moser, S. (2021) Tetrapyrrolic Pigments from Heme- and Chlorophyll Breakdown are Actin-Targeting Compounds. Angewandte Chemie International Edition 60(41): 10.1002/anie.202107813.
- Kretschmer, M.; Kadlubowska, P.; Hoffmann, D.; Schwalbe, B.; Auerswald, H.; Schreiber, M. (2020) Zikavirus pr ME Envelope Pseudotyped Human Immunodeficiency Virus Type-1 as a Novel Tool for Glioblastoma-Directed Virotherapy. Cancers 12(1000): 10.3390/cancers12041000