Publications

2023

• Borgmeyer M, Andres-Alonso M, Mirzapourdelavar H, Lormann J, Klein K, Schweizer M, Hoffmeister-Ullerich S, Oelschlegel AM, Dityatev A, Kreutz MR. Golgi satellites are essential for polysialylation of NCAM and expression of LTP at distal synapses. Cell Rep 2023 Jul 25 doi: 10.1016/j.celrep.2023.112692

2021 

• Baeken MW, Schwarz M, Kern A, Moosmann B, Hajieva P, Behl C. The selective degradation of sirtuins via macroautophagy in the MPP + model of Parkinson's disease is promoted by conserved oxidation sites. Cell Death Discov 2021; 7(1):286. 

• Heymans V, Kunath S, Hajieva P, Moosmann B. Cell culture characterization of prooxidative chain-transfer agents as novel cytostatic drugs. Molecules 2021; 26(21): 6743. 

• Wolff L, Bandaru SSM, Eger E, Lam H-N, Napierkowski M, Baecker D, Schulzke C, Bednarski PJ. Comprehensive Evaluation of Biological Effects of Pentathiepins on Various Human Cancer Cell Lines and Insights into Their Mode of Action. Int J Mol Sci 2021; 22(14):7631.

• Baumann R, Untersmayr E, Zissler UM, Eyerich S, Adcock IM, Brockow K, Biedermann T, Ollert M, Chaker AM, Pfaar O, Garn H, Thwaites RS, Togias A, Kowalski ML, Hansel T, Jakwerth C, Schmidt- Weber CB: Non-invasive and minimally-invasive techniques for the diagnosis and management of allergic diseases. EAACI position paper. Allergy 2021; 76(4):1010-1023. 

• Van Broeckhoven J, Sommer D, Dooley D, *Hendrix S, *Franssen AJPM: Macrophage phagocytosis after spinal cord injury: when friends become foes. Brain 2021 Jul 9: awab250. *equal contribution.

• Aguilera-Lizarraga J, Florens MV, Viola MF, Jain P, Decraecker L, Appeltans I, Cuende-Estevez M, Fabre N, Van Beek K, Perna E, Balemans D, Stakenborg N, Theofanous S, Bosmans G, Mondelaers SU, Matteoli G, Ibiza Martínez S, Lopez-Lopez C, Jaramillo-Polanco J, Talavera K, Alpizar YA, Feyerabend TB, Rodewald HR, Farre R, Redegeld FA, Si J, Raes J, Breynaert C, Schrijvers R, Bosteels C, Lambrecht BN, Boyd SD, Hoh RA, Cabooter D, Nelis M, Augustijns P, Hendrix S, Strid J, Bisschops R, Reed DE, Vanner SJ, Denadai-Souza A, Wouters MM, Boeckxstaens GE. Local immune response to food antigens drives meal-induced abdominal pain. Nature 2021; 590(7844):151-156.

• Ambrozkiewicz MC, Borisova E, Schwark M, Ripamonti S, Schaub T, Smorodchenko A, Weber AI, Rhee HJ, Altas B, Yilmaz R, Mueller S, Piepkorn L, Horan ST, Straussberg R, Zaqout S, Jahn O, Dere E, Rosário M, Boehm-Sturm P, Borck G, Willig KI, Rhee J, Tarabykin V, Kawabe H. The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc. Mol Psychiatry. 2021 Jun;26(6):1980-1995.

2020

• Baeken MW, Moosmann B, Hajieva P. Retrotransposon activation by distressed mitochondria in neurons. Biochem Biophys Res Commun 2020; 525: 570-575.

• Baeken MW, Weckmann K, Diefenthäler P, Schulte J, Yusifli K, Moosmann B, Behl C, Hajieva P. Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C. Cells 2020; 9(10):2315. 

• Kunath S, Schindeldecker M, De Giacomo A, Meyer T, Sohre S, Hajieva P, von Schacky C, Urban J, Moosmann B. Prooxidative chain transfer activity by thiol groups in biological systems. Redox Biol 2020; 36:101628.  

• Millward JM, Ramos Delgado P, Smorodchenko A, Boehmert L, Periquito J, Reimann HM, Prinz C, Els A, Scheel M, Bellmann-Strobl J, Waiczies H, Wuerfel J, Infante-Duarte C, Chien C, Kuchling J, Pohlmann A, Zipp F, Paul F, Niendorf T, Waiczies S. (2020) Transient enlargement of brain ventricles during relapsing-remitting multiple sclerosis and experimental autoimmune encephalomyelitis. JCI Insight 5;5(21):e140040.  

• Szczepek AJ, Dudnik T, Karayay B, Sergeeva V, Olze H, Smorodchenko A. (2020) Mast Cells in the Auditory Periphery of Rodents. Brain Sci. 1;10(10): 697.  

• Bassiouni M, Stölzel K, Smorodchenko A, Olze H, Szczepek AJ. (2020) Tackling the Mouse-on-Mouse Problem in Cochlear Immunofluorescence: A Simple Double-Blocking Protocol for Immunofluorescent Labeling of Murine Cochlear Sections with Primary Mouse Antibodies. Curr Protoc Mouse Biol 10(4): e84.  

• Moosmann B, Schindeldecker M, Hajieva P. Cysteine, glutathione and a new genetic code: biochemical adaptations of the primordial cells that spread into open water and survived biospheric oxygenation. Biol Chem.2020;401(2):213-231. 

• Jankauskaitė E, Ambroziak   AM, Hajieva P, Ołdak M, Tońska K, Korwin M, Bartnik E, Kodroń A. Testosterone increases apoptotic cell death and decreases mitophagy in Leber's hereditary optic neuropathy cells. J Appl Genet 2020; 61(2):195-203.

• Grajchen E, Wouters E, van de Haterd B, Haidar M, Hardonnière K, Dierckx T, Van Broeckhoven J, Erens C, Hendrix S, Kerdine-Römer S, Hendriks JJA, Bogie JFJ. CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation. J Neuroinflammation 2020; 17(1):224.

• Quarta A, Meese T, Pieters Z, Van Breedam E, Le Blon D, Van Broeckhoven J, Hendrix S, Goossens H, Hens N, Berneman Z, Van Nieuwerburgh F, Ponsaerts P. Murine induced pluripotent stem cell-derived neuroimmune cell culture models emphasize opposite immune-effector functions of interleukin 13-primed microglia and macrophages in terms of neuroimmune toxicity. Glia 2021; 69(2):326-345.

• Hendrix S, Sanchez S, Ventriglia E, Lemmens S. HDAC8 Inhibition Reduces Lesional Iba-1+ Cell Infiltration after Spinal Cord Injury without Effects on Functional Recovery. Int J Mol Sci. 2020; 21(12):4539.  

• Lemmens S, Nelissen S, Dooley D, Geurts N, Hendrix S. Stress pathway modulation is detrimental or ineffective for functional recovery after spinal cord injury in mice. J Neurotrauma 2020; 37(3):564-571. 

• Calvopina, D.A., Noble, C., Weis, A., Hartel, G.F., Ramm, L.E., Balouch, F., Fernandez-Rojo, M.A., Coleman, M.A., Lewindon, P.J. and Ramm, G.A. Supersonic shear-wave elastography and APRI for the detection and staging of liver disease in pediatric cystic fibrosis. Journal of Cystic Fibrosis, 2020;19(3), pp.449-454.

• Balewski Ł, Sączewski F, Bednarski PJ, Wolff L, Nadworska A, Gdaniec M, Kornicka A. Synthesis, Structure and Cytotoxicity Testing of Novel 7-(4,5-dihydro-1H-imidazol-2-yl)-2-aryl-6,7-dihydro-2H-imidazo[2,1-c][1,2,4]triazol-3(5H)-Imine Derivatives. Molecules 2020; 25(24):5924.

• Behnisch-Cornwell S, Wolff L, Bednarski PJ. The Effect of Glutathione Peroxidase-1 Knockout on Anticancer Drug Sensitivities and Reactive Oxygen Species in Haploid HAP-1 Cells. Antioxidants 2020; 9(12):1300.

• Behnisch-Cornwell S, Bandaru SSM, Napierkowski M, Wolff L, Zubair M, Urbainsky C, Lillig C, Schulzke C, Bednarski PJ. Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells. ChemMedChem 2020; 15(16):1515-1528.

• Wilpert NM, Krueger M, Opitz R, Sebinger DD, Paisdzior S, Mages B, Schulz A, Spranger J, Wirth EK, Stachelscheid H, Mergenthaler P, Vajkoczy P, Krude H, Kühnen P, Bechmann I, Biebermann H. Spatiotemporal Changes of Cerebral Monocarboxylate Transporter 8 Expression. Thyroid 2020; 30(9):1366-1383.

2019

• Babazada H, Alekberli T, Hajieva P, Farajov E.  Biosensor-based kinetic and thermodynamic characterization of opioids interaction with human μ-opioid receptor. Eur J Pharm Sci. 2019; 138:105017.  

• Sommer D, Corstjens I, Sanchez S, Dooley D, Lemmens S, Van Broeckhoven J, Bogie J, Vanmierlo T, Vidal PM, Rose-John S, Gou-Fabregas M, Hendrix S. ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury.
  Brain, Behavior, and Immunity, 2019; 80:129-145.

• Vangansewinkel T, Lemmens S, Geurts N, Quanten K, Dooley D, Pejler G, Hendrix S. Mouse mast cell protease 4 suppresses scar formation after traumatic spinal cord injury. Scientific Reports, 2019; 9:3715.

• Kodroń A, Hajieva P, Kulicka A, Paterczyk B, Jankauskaite E, Bartnik E. Analysis of BNIP3 and BNIP3L/Nix expression in cybrid cell lines harboring two LHON-associated mutations. Acta Biochim Pol. 2019; 66(4):427-435. 

• Giesecke T, Himmerkus N, Leipziger J, Bleich M, Koshimizu TA, Fähling M, Smorodchenko A, Shpak J, Knappe C, Isermann J, Ayasse N, Kawahara K, Schmoranzer J, Gimber N, Paliege A, Bachmann S, Mutig K. Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells. J Am Soc Nephrol. 2019; 30(6):946-961.

• Weis, A., Marquart, L., Calvopina, D.A., Genz, B., Ramm, G.A. and Skoien, R. Serum microRNAs as biomarkers in hepatitis C: preliminary evidence of a microRNA panel for the diagnosis of hepatocellular carcinoma. Int J Mol Sci, 2019;20(4), p.864.

• Lewindon, P.J., Puertolas-Lopez, M.V., Ramm, L.E., Noble, C., Pereira, T.N., Wixey, J.A., Hartel, G.F., Calvopina, D.A., Leung, D.H. and Ramm, G.A. Accuracy of transient elastography data combined with APRI in detection and staging of liver disease in pediatric patients with cystic fibrosis. Clinical Gastroenterology and Hepatology, 2019;17(12), pp.2561-2569.

• Genz, B., Coleman, M.A., Irvine, K.M., Kutasovic, J.R., Miranda, M., Gratte, F.D., Tirnitz-Parker, J.E., Olynyk, J.K., Calvopina, D.A., Weis, A. and Cloonan, N.. Overexpression of miRNA- 25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells. Sci Rep, 2019;9(1), pp.1-18. 

• Makowska A, Wolff L, Sączewski F, Bednarski PJ, Kornicka A. Synthesis and cytotoxic evaluation of benzoxazole/benzothiazole-2-imino-coumarin hybrids and their coumarin analogues as potential anticancer agents. Pharmazie 2019; 74(11):648-657. 

2018

• Baumann R, Brand P, Chaker A, Markert A, Rack I, Davatgarbenam S, Joraslafsky S, Gerhards B, Kraus T, Gube M: Human nasal mucosal C-reactive protein responses after inhalation of ultrafine welding fume particles: positive correlation to systemic C-reactive protein responses. Nanotoxicology, 2018; 12:1130-1147. 

• Baumann R, Gube M, Markert A, Davatgarbenam S, Kossack V, Gerhards B, Kraus T, Brand P: Systemic serum amyloid A as a biomarker for exposure to zinc and/or copper containing metal fumes. Journal of Exposure Science and Environmental Epidemiology, 2018; 28: 84–91.

• Hajieva P, Baeken MW, Moosmann B The role of Plasma Membrane Calcium ATPases (PMCAs) in neurodegenerative disorders. Neurosci Lett. 2018; 663:29-38.

• Dudeck A, Köberle M, Goldmann O, Meyer N, Dudeck J, Lemmens S, Rohde M, Roldán NG, Dietze-Schwonberg K, Orinska Z, Medina E, Hendrix S, Metz M, Zenclussen AC, von Stebut E, Biedermann T: Mast cells as protectors of health. Journal of Allergy and Clinical Immunology, 2019; 144(4S): S4-S18.

• Sanchez S, Lemmens S, Baeten P, Sommer D, Dooley D, *Hendrix S, *Gou Fabregas, M. HDAC3 inhibition promotes alternative activation of macrophages but does not affect functional recovery after spinal cord injury. Experimental Neurobiology, 2018; 27(5):437-452.

• Weckmann K, Diefenthäler P, Baeken MW, Yusifli K, Turck CW, Asara JM, Behl C, Hajieva P. Metabolomics profiling reveals differential adaptation of major energy metabolism pathways associated with autophagy upon oxygen and glucose reduction. Sci Rep 2018; 8: 2337.

• Granold M, Hajieva P, Tosa M, Irimie FD, Moosmann B. Modern diversification of the amino acid repertoire driven by oxygen. Proc Natl Acad Sci USA 2018; 115: 41-46.

• Calvopina, D.A., Chatfield, M.D., Weis, A., Coleman, M.A., Fernandez-Rojo, M.A., Noble, C., Ramm, L.E., Leung, D.H., Lewindon, P.J. and Ramm, G.A. miRNA-Seq identifies a serum miRNA panel, which combined with APRI can detect and monitor liver disease in paediatric Cystic Fibrosis. Hepatology, 2018; 68(6), pp.2301-2316.